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@#【Objective】To explore the characteristics of social cognitive impairment in patients with stable schizophrenia ，and to analyze the influencing factors to provide a clinical coping strategy for improving the social cognitive function of patients with schizophrenia.【Methods】Firstly，both 158 stable schizophrenia patients and 40 healthy controls took the test of MATRICS Consensus Cognitive Battery （MCCB） and the Brief Psychiatric Rating Scale （BPRS）. General demographic information and clinical data of subjects were collected using questionnaire. Then ，the overall cognitive function and social cognitive function between schizophrenia patients and healthy controls were compared to explore the related factors affecting the social cognitive function of patients with schizophrenia.【Results】①Overall MCCB score and Mayer-Salovey-Caruso Emotional Intelligence Test（MSCEIT）factor score of schizophrenia patients with stable period were significantly lower than those of healthy control group（P < 0.05）；②The social cognitive function of schizophrenia patients was significantly correlated with gender，age，hostile suspicion，continuous performance and category fluency （P < 0.05）. 【Conclusions】 Compared with the healthy control group ，schizophrenia patients with stable period have impairment of social cognitive function ，and significant impairment of overall cognitive function. The social cognitive function of schizophrenia patients with stable period is significantly affected by gender ，age ，hostility suspicion ，and neurocognitive function（attention and information processing speed）.
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OBJECTIVE@#Increased carotid artery intima-media thickness (CIMT) and carotid plaque as manifestations of carotid atherosclerosis have been used as markers of cardiovascular disease (CVD). The components of metabolic syndrome (MetS) are linked to CVD, but the association between MetS and CVD is controversial.@*METHODS@#A total of 8,933 Chinese adults aged 40 years or older from 2010 to 2014 were selected from the Jidong and Kailuan communities. MetS was defined by the International Diabetes Federation criteria. CIMT and carotid plaque were measured using color Doppler ultrasound. Logistic regression models were used to assess the association of MetS with carotid plaque and CIMT.@*RESULTS@#MetS was found among 3,461 (3,461/8,933) participants. The odds ratio and 95% confidence internal (CI) for carotid plaques in participants with MetS was 1.16 (1.03-1.30). The risk of carotid plaques increased with the number of MetS components. The average CIMT was higher in participants with MetS (β = 0.020, 95% CI, 0.014-0.027) and in participants with more MetS components.@*CONCLUSION@#Individuals with MetS are at an increased risk for carotid atherosclerosis compared to those without MetS.
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<p><b>BACKGROUND</b>In-hospital medical complications are associated with poorer clinical outcomes for stroke patients after disease onset. However, few studies from China have reported the effect of these complications on the mortality of patients with acute ischemic stroke. In this prospective work, the China National Stroke Registry Study, we investigated the effect of medical complications on the case fatality of patients with acute ischemic stroke.</p><p><b>METHODS</b>From September 2007 to August 2008, we prospectively obtained the data of patients with acute stroke from 132 clinical centers in China. Medical complications, case fatality and other information recorded at baseline, during hospitalisation, and at 3, 6, and 12 months after stroke onset. Multivariable Logistic regression was performed to analyze the effect of medical complications on the case fatality of patients with acute ischemic stroke.</p><p><b>RESULTS</b>There were 39 741 patients screened, 14 526 patients with acute ischemic stroke recruited, and 11 560 ischemic stroke patients without missing data identified during the 12-month follow-up. Of the 11 560 ischemic patients, 15.8% (1826) had in-hospital medical complications. The most common complication was pneumonia (1373; 11.9% of patients), followed by urinary tract infection and gastrointestinal bleeding. In comparison with patients without complications, stroke patients with complications had a significantly higher risk of death during their hospitalization, and at 3, 6 and 12 months post-stroke. Having any one in-hospital medical complication was an independent risk factor for death in patients with acute ischemic stroke during hospital period (adjusted OR = 6.946; 95%CI 5.181 to 9.314), at 3 months (adjusted OR = 3.843; 95%CI 3.221 to 4.584), 6 months (adjusted OR = 3.492; 95%CI 2.970 to 4.106), and 12 months (adjusted OR = 3.511; 95%CI 3.021 to 4.080). Having multiple complications strongly increased the death risk of patients.</p><p><b>CONCLUSION</b>Short-term and long-term outcomes of acute stroke patients are affected by in-hospital medical complications.</p>